ANUA Niacinamide 10% +TXA 4% Serum

Treat

AM/PM

Array

Water Gel

100% Fragrance-Free

Formulated with high-potency 10% Niacinamide and 4% Tranexamic Acid at physiological skin pH (5.5–6.2). Co-layering immediately with unbuffered, low-pH direct chemical exfoliants (AHA/BHA) or unbuffered pure L-Ascorbic Acid (pH < 3.5) drives acid-catalyzed hydrolysis of Niacinamide into free Nicotinic Acid (niacin). In Egypt's intense summer heat (38–42°C), this triggers acute peripheral vasomotor flushing, capillary engorgement, and marked neurosensory stinging. Furthermore, combining multi-pathway depigmenting actives with aggressive peeling agents on compromised tissue risks barrier collapse and catastrophic rebound Post-Inflammatory Hyperpigmentation (PIH). Clinical Protocol: Maintain strict temporal separation by applying this serum in morning rituals beneath high broad-spectrum photoprotection, while partitioning intensive chemical peels or prescription retinoids to alternate evenings. Always apply onto 100% dry skin—residual moisture accelerates trans-epidermal flux, precipitating tingling—and respect the mandatory 3-minute absorption window to prevent cosmetic pilling under sunscreen and makeup.

Broad-Spectrum Photoprotective Sunscreens (SPF 50+ / PA++++ Mineral & Chemical Filters), Physiological Ceramides (Ceramide NP, AP, EOP) & Barrier Lipids, Centella Asiatica (Cica), Madecassoside & Asiaticoside Complexes, Multi-Molecular Hyaluronic Acid & Polyglutamic Acid Complexes, Panthenol (Pro-Vitamin B5) & Allantoin (Tissue Soothing & Hydration), Alpha-Arbutin & Glutathione (Multi-Pathway Melanogenesis Suppression), Biomimetic Squalane & Non-Comedogenic Barrier Lipids, Topical Retinoids (Alternated on cycling evenings, not co-layered simultaneously)

Apply only to completely dry skin.