Numbuzin No.2 Rose PDRN Collagen Plumping Serum

Treat

AM/PM

Array

Water Gel

100% Fragrance-Free

Direct chemical keratolytics formulated at an unbuffered low pH (<3.8), such as high-strength Alpha Hydroxy Acids (Glycolic, Lactic) and Beta Hydroxy Acids (Salicylic Acid), alongside unbuffered pure L-Ascorbic Acid, provoke acid-catalyzed hydrolysis of the amide bonds within the Multi-Peptide Matrix and denature the delicate tertiary bio-signaling conformation of Rose PDRN. Concurrently, strong oxidative agents such as Benzoyl Peroxide trigger oxidative cleavage of nucleotide chains. Under Egyptian environmental realities—distinguished by hyperthermic summer heatwaves (38–42°C), extreme UV indices (10–12), and mineral-dense tap water (Cairo and Alexandria 200–800 ppm CaCO3 hardness)—simultaneous unbuffered acidic layering disrupts the epidermal barrier and accelerates trans-epidermal water loss (TEWL). In indoor air-conditioned spaces where ambient moisture is stripped, unsealed humectants risk reverse osmotic water depletion, mandating a breathable physiological barrier emulsion. To eliminate cosmetic pilling ('بيفرول') under intense coastal humidity, an essential resting window of 3 to 5 minutes must be observed before layering broad-spectrum photoprotection (SPF 50+) or makeup.

Niacinamide (Vitamin B3 ≤ 5%), Physiological Ceramides (NP, AP, EOP) & Barrier Lipids, Multi-Molecular Weight Hyaluronic Acid & Polyglutamic Acid, Centella Asiatica (Cica) & Titrated Madecassoside Triterpenes, Topical Retinoids & Retinaldehyde (Sequential nocturnal layering / Sandwich buffering), Ectoin & Bifida Ferment Lysate, Broad-Spectrum Photoprotection (SPF 50+ / PA++++ Mineral & Hybrid Filters)