Numbuzin No.9 NMN+ Bio Lifting-Sil Essence

Treat

AM/PM

Array

Dewy Glow

100% Fragrance-Free

Formulated with an intricate bio-tensile silk matrix comprising 50 multi-peptides, low-molecular collagen, and mitochondrial Nicotinamide Mononucleotide (NMN), this essence relies on delicate amide linkages and higher-order structural conformations to stimulate dermal tension and NAD+ biosynthesis. Co-applying or layering concurrently with direct unbuffered keratolytics formulated at a low pH (<3.8)—such as Alpha Hydroxy Acids (Glycolic Acid, Lactic Acid), Beta Hydroxy Acids (Salicylic Acid), or unbuffered pure L-Ascorbic Acid (Vitamin C <3.5)—triggers rapid acid-catalyzed amide hydrolysis, cleaving the signaling peptides and irreversibly neutralizing the formula's structural lifting efficacy. Furthermore, strong oxidizing agents such as Benzoyl Peroxide cause oxidative denaturation of the peptide and nucleotide bonds. Grounded in Egyptian environmental dermatological realities—characterized by extreme ambient summer heat (38–42°C), high UV index (10–12), desiccating indoor air conditioning, and highly calcareous domestic tap water (Cairo and Alexandria mineral hardness 200–800 ppm CaCO3)—destabilizing the epidermal barrier with acidic mismatches exacerbates trans-epidermal water loss (TEWL) and provokes acute vasomotor erythema. To ensure seamless biopolymer adherence and prevent cosmetic pilling ('بيفرول') under broad-spectrum photoprotective shields (SPF 50+) or makeup, patients must strictly observe a 3 to 5-minute absorption stabilization window, applying with warm palms via gentle upward micro-pressing rather than vigorous mechanical friction.

Topical Retinoids (Tretinoin, Retinaldehyde, Retinol – Exceptional Nocturnal Tensor Synergy), Niacinamide (Vitamin B3 ≤ 5%) & Cellular Bio-Coenzymes, Multi-Molecular Weight Hyaluronic Acid & Polyglutamic Acid, Physiological Ceramides (NP, AP, EOP), Phytosphingosine & Barrier Lipids, Centella Asiatica (Cica), Madecassoside & Asiaticoside Soothing Fractions, Ectoin & Fermentation Lysates (Bifida, Galactomyces), Broad-Spectrum Photoprotection (SPF 50+ / PA++++ Mineral & Hybrid Shields), Biomimetic Squalane & Non-Comedogenic Barrier Emulsions

Apply only to completely dry skin.